By George M. Rodgers
This entire quantity discusses the protease ADAMTS13, summarizing the present prestige of uncomplicated and scientific examine. The 9 authoritative chapters commence with a old point of view by means of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its common functionality in hemostasis (cleavage of von Willebrand factor). rising study topics for ADAMTS13 are lined, together with its capability position in angiogenesis and different elements of mobile biology. extra subject matters comprise laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and bought ADAMTS13 deficiency. A bankruptcy on similar thrombotic microangiopathic (TMA) problems examines the variations among TMAs linked to ADAMTS13 deficiency and people no longer linked to ADAMTS13 deficiency. a last bankruptcy studies the initial info on rising elements of ADAMTS13, corresponding to the prestige of recombinant ADAMTS13 items and their strength utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and ailment is an important source for scientific hematologists, transfusion medication physicians, and researchers attracted to hemostasis, vascular biology, biochemistry, and metalloproteases.
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ADAMTS13: Biology and Disease by George M. Rodgers